Blar i forfatter "Schniers, Armin"

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    • The proteome of ulcerative colitis - Functional analyses of the active disease and the remission state in comparison with healthy controls 

      Schniers, Armin (Doctoral thesis; Doktorgradsavhandling, 2019-06-18)
      This work characterizes the proteome of human colon mucosa in ulcerative colitis (UC). We developed an optimized sample preparation method of colon mucosa biopsies for bottom-up proteomics and applied it to characterize the proteomes of active UC, remission from UC, and healthy controls. Abundances of proteins related to the immune system and to protein processing in the endoplasmic reticulum ...

    • Ulcerative colitis: Functional analysis of the in-depth proteome 

      Schniers, Armin; Goll, Rasmus; Pasing, Yvonne; Sørbye, Sveinung; Florholmen, Jon; Hansen, Terkel (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-01-29)
      <p><i>Background - </i>Ulcerative colitis (UC) is one major form of inflammatory bowel disease. The cause and the pathophysiology of the disease are not fully understood and we therefor aim in this study to identify important pathophysiological features in UC from proteomics data. <p><i>Methods - </i>Colon mucosa biopsies from inflamed tissue of untreated UC patients at diagnosis and from healthy ...